a physical condition in which there is a disturbance of normal functioning

unable to develop a normal immune response usually because of malnutrition or immunodeficiency or immunosuppressive therapy

immunological disorder in which some part of the body's immune system is inadequate and resistance to infectious diseases is reduced

lowering the body's normal immune response to invasion by foreign substances; can be deliberate (as in lowering the immune response to prevent rejection of a transplanted organ) or incidental (as a side effect of radiotherapy or chemotherapy for cancer)

reduction or lack of an immune response to a specific antigen